Publikationen
Publikationen
Originalarbeiten
[23] Reinartz, A., Ehling, J., Leue, A., Liedtke, C., Schneider, U., Kopitz, J., Weiss, T., Hellerbrand, C., Weiskirchen, R., Knuchel, R., et al. (2010). Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis. Biochim Biophys Acta.
[22] Bettermann, K., Vucur, M., Haybaeck, J., Koppe, C., Janssen, J., Heymann, F., Weber, A., Weiskirchen, R., Liedtke, C., Gassler, N., et al. (2010). TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer Cell 17, 481-496.
[21] Freimuth, J., Gassler, N., Moro, N., Gunther, R.W., Trautwein, C., Liedtke, C., and Krombach, G.A. (2010). Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma. Mol Cancer 9, 94.(IF 2008: 5,36)
[20] Kroy, D.C., Beraza, N., Tschaharganeh, D.F., Sander, L.E., Erschfeld, S., Giebeler, A., Liedtke, C., Wasmuth, H.E., Trautwein, C., and Streetz, K.L. (2010). Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice. Hepatology 51, 463-473 (IF 2008: 11,355).
[19] Amann, T., Bataille, F., Spruss, T., Dettmer, K., Wild, P., Liedtke, C., Muhlbauer, M., Kiefer, P., Oefner, P.J., Trautwein, C., et al. (2010). Reduced Expression of Fibroblast Growth Factor Receptor 2IIIb in Hepatocellular Carcinoma Induces a More Aggressive Growth. Am J Pathol 176, 1433-1442 (IF 2006: 5,697).
[18] Nevzorova, Y.A., Tschaharganeh, D., Gassler, N., Geng, Y., Weiskirchen, R., Sicinski, P., Trautwein, C., and Liedtke, C. (2009). Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin. Gastroenterology 137, 691-703, 703 e691-696 (IF 2008: 12,716).
[17] Beraza, N., Malato, Y., Sander, L.E., Al-Masaoudi, M., Freimuth, J., Riethmacher, D., Gores, G.J., Roskams, T., Liedtke, C., and Trautwein, C. (2009). Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage. J Exp Med 206, 1727-1737 (IF 2008: 15,463).
[16] Malato, Y., Sander, L.E., Liedtke, C., Al-Masaoudi, M., Tacke, F., Trautwein, C., and Beraza, N. (2008). Hepatocyte-specific inhibitor-of-kappaB-kinase deletion triggers the innate immune response and promotes earlier cell proliferation during liver regeneration. Hepatology 47, 2036-2050 (IF 2008: 11,355).
[15] Dierssen, U., Beraza, N., Lutz, H.H., Liedtke, C., Ernst, M., Wasmuth, H.E., and Trautwein, C. (2008). Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration. J Biol Chem 283, 9886-9895 (IF 2006:5,520).
[14] Beraza, N., Malato, Y., Vander Borght, S., Liedtke, C., Wasmuth, H.E., Dreano, M., de Vos, R., Roskams, T., and Trautwein, C. (2008). Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis. Gut 57, 655-663 (IF 2006: 9,766).
[13] Liedtke, C., Lambertz, D., Schnepel, N., and Trautwein, C. (2007). Molecular mechanism of Mitomycin C-dependent caspase-8 regulation: implications for apoptosis and synergism with interferon-alpha signalling. Apoptosis 12, 2259-2270 (IF 2007: 3,421).
[12] Lehnardt, S., Wennekamp, J., Freyer, D., Liedtke, C., Krueger, C., Nitsch, R., Bechmann, I., Weber, J.R., and Henneke, P. (2007). TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia. J Immunol 179, 6134-6143 (IF 2007: 6,068).
[11] Zschemisch, N.H., Liedtke, C., Dierssen, U., Nevzorova, Y.A., Wustefeld, T., Borlak, J., Manns, M.P., and Trautwein, C. (2006). Expression of a cyclin E1 isoform in mice is correlated with the quiescent cell cycle status of hepatocytes in vivo. Hepatology 44, 164-173 (IF 2006: 10,446).
[10] Liedtke, C., Groger, N., Manns, M.P., and Trautwein, C. (2006). Interferon-alpha enhances TRAIL-mediated apoptosis by up-regulating caspase-8 transcription in human hepatoma cells. J Hepatol 44, 342-349 (IF 2006: 6,073).
[09] Tacke, F., Liedtke, C., Bocklage, S., Manns, M.P., and Trautwein, C. (2005). CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter. Gut 54, 1309-1317 (IF 2005: 7,692).
[8] Liedtke, C., Zschemisch, N.H., Cohrs, A., Roskams, T., Borlak, J., Manns, M.P., and Trautwein, C. (2005). Silencing of caspase-8 in murine hepatocellular carcinomas is mediated via methylation of an essential promoter element. Gastroenterology 129, 1602-1615 (IF 2005: 12,386).
[7] Vogel, C.F., Sciullo, E., Park, S., Liedtke, C., Trautwein, C., and Matsumura, F. (2004). Dioxin increases C/EBPbeta transcription by activating cAMP/protein kinase A. J Biol Chem 279, 8886-8894 (IF 2004: 6,355).
[6] Zender, L., Hutker, S., Liedtke, C., Tillmann, H.L., Zender, S., Mundt, B., Waltemathe, M., Gosling, T., Flemming, P., Malek, N.P., et al. (2003). Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci U S A 100, 7797-7802 (IF 2003: 10,727).
[5] Liedtke, C., Groger, N., Manns, M.P., and Trautwein, C. (2003). The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism. J Biol Chem 278, 27593-27604 (IF 2003: 6,482).
[4] Liedtke, C., Plumpe, J., Kubicka, S., Bradham, C.A., Manns, M.P., Brenner, D.A., and Trautwein, C. (2002). Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology 36, 315-325 (IF 2002: 9,825).
[3] Ludde, T., Kubicka, S., Plumpe, J., Liedtke, C., Manns, M.P., and Trautwein, C. (2001). Ras adenoviruses modulate cyclin E protein expression and DNA synthesis after partial hepatectomy. Oncogene 20, 5264-5278 (IF 2001: 6,737).
[2] Liedtke, C., and Schmidt, H. (1998). Molecular cloning and sequence analysis of the Schizosaccharomyces pombe ade10+ gene. Yeast 14, 1307-1310 (IF 1998: 2,221).
[1] Michael, H., Schmidt, H., Fleck, O., Gutz, H., Liedtke, C., Lorentz, A., and Ostermann, K. (1994). The mating-type region of Schizosaccharomyces pombe contains an essential gene encoding a protein homologous to human modulators of HIV transactivation. Gene 145, 205-210 (IF 1994: 2,305).
Übersichtsartikel und Buchbeiträge
[9] Weiskirchen, R., Liedtke, C., and Trautwein, C. (2009). When sleeping beauty wakes up and jumps into a cancer-minded environment. Hepatology 49, 2122-2124.
[8] Liedtke, C., and Trautwein, C. (2008). A dual role of p21 in liver regeneration and hepatocarcinogenesis. Hepatology 48, 1713-1714.
[7] Sander, L.E., Trautwein, C., and Liedtke, C. (2007). Is interleukin-6 a gender-specific risk factor for liver cancer? Hepatology 46, 1304-1305.
[6] Liedtke, C., and Streetz, K.L. (2007). Hepatocytes from embryonic stem cells: Prometheus revisited? Hepatology 45, 829-830.
[5] Liedtke, C., and Trautwein, C. (2006). The role of JNK2 in toxic liver injury. J Hepatol 45, 762-764.
[4] Trautwein, C., Liedtke, C., Streetz, K.L.S., Luedde, T., and Klein, C. (2005). Acute liver failure – mechanisms of liver cell destruction. In Falk Symposium 146 on Gut-Liver Interactions – Basic and Clinical Concepts, R.S. Blumberg, A. Gangl, M.P. Manns, H. Tilg, and M. Zeitz, eds. (Innsbruck, AUSTRIA, Springer), pp. 253-263.
[3] Liedtke, C., and Trautwein, C. (2004). A protective role of Stat3 in Fas mediated apoptosis of the liver. J Hepatol 40, 874-875.
[2] Luedde, T., Liedtke, C., Manns, M.P., and Trautwein, C. (2002). Losing balance: cytokine signaling and cell death in the context of hepatocyte injury and hepatic failure. Eur Cytokine Netw 13, 377-383.
[1] Streetz, K., Liedtke, C., Manns, M.P., and Trautwein, C. (1999). Role of TNF-alpha-dependent pathways in models of acute liver failure. In Falk Symposium on Cytokines and Cell Homeostasis in the Gastrointestinal Tract, T. Andus, G. Rogler, K. Schlottmann, E. Frick, G. Adler, M. Zeitz, W. Schmiegel, and J. Scholmerich, eds. (Regensburg, Germany, Springer), pp. 159-170.